K66M (p.Lys66Met) variant of NLRP3 (Q96P20)
K66M (p.Lys66Met) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
K66M (p.Lys66Met) variant details
- p.Lys66Met
- gnomAD 1-247418991-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.20
- CADD 23.10
- PolyPhen-2 0.70
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available