K23N (p.Lys23Asn) variant of NLRP3 (Q96P20)
K23N (p.Lys23Asn) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
K23N (p.Lys23Asn) variant details
- p.Lys23Asn
- gnomAD 1-247418866-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.31
- CADD 22.10
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available