I59M (p.Ile59Met) variant of NLRP3 (Q96P20)
I59M (p.Ile59Met) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
I59M (p.Ile59Met) variant details
- p.Ile59Met
- rs773673175
- gnomAD 1-247418971-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.2
- REVEL 0.29
- CADD 1.07
- PolyPhen-2 0.99
- SIFT 0.40
- Population evidence available
- Structural context available
- Literature evidence available