H51R (p.His51Arg) variant of NLRP3 (Q96P20)
H51R (p.His51Arg) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
H51R (p.His51Arg) variant details
- p.His51Arg
- rs367663649
- gnomAD 1-247418946-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.116
- REVEL 0.05
- CADD 4.03
- PolyPhen-2 0.01
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available