H28Y (p.His28Tyr) variant of NLRP3 (Q96P20)
H28Y (p.His28Tyr) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data, published literature, and structural context.
H28Y (p.His28Tyr) variant details
- p.His28Tyr
- rs763551829
- gnomAD 1-247418876-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.128
- REVEL 0.04
- CADD 5.43
- PolyPhen-2 0.01
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available