G95C (p.Gly95Cys) variant of NLRP3 (Q96P20)
G95C (p.Gly95Cys) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
G95C (p.Gly95Cys) variant details
- p.Gly95Cys
- gnomAD 1-247419077-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.246
- REVEL 0.11
- CADD 23.80
- PolyPhen-2 0.07
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available