F61L (p.Phe61Leu) variant of NLRP3 (Q96P20)
F61L (p.Phe61Leu) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data, published literature, and structural context.
F61L (p.Phe61Leu) variant details
- p.Phe61Leu
- gnomAD 1-247418975-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.274
- REVEL 0.15
- CADD 23.10
- PolyPhen-2 0.47
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available