E91K (p.Glu91Lys) variant of NLRP3 (Q96P20)
E91K (p.Glu91Lys) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
E91K (p.Glu91Lys) variant details
- p.Glu91Lys
- rs777250607
- gnomAD 1-247419065-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.13
- CADD 15.20
- PolyPhen-2 0.01
- SIFT 0.15
- Population evidence available
- Structural context available
- Literature evidence available