E91D (p.Glu91Asp) variant of NLRP3 (Q96P20)
E91D (p.Glu91Asp) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
E91D (p.Glu91Asp) variant details
- p.Glu91Asp
- gnomAD 1-247419067-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.06
- CADD 7.79
- PolyPhen-2 0.01
- SIFT 0.39
- Population evidence available
- Structural context available
- Literature evidence available