D60N (p.Asp60Asn) variant of NLRP3 (Q96P20)
D60N (p.Asp60Asn) in NLRP3 (Q96P20) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
D60N (p.Asp60Asn) variant details
- p.Asp60Asn
- rs1131691891
- gnomAD 1-247418972-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.03
- CADD 20.50
- PolyPhen-2 0.35
- SIFT 0.32
- Population evidence available
- Structural context available
- Literature evidence available