T30S (p.Thr30Ser) variant of NLGN4X (Neuroligin-4, X-linked)
T30S (p.Thr30Ser) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
T30S (p.Thr30Ser) variant details
- p.Thr30Ser
- ExAC rs778834918
- gnomAD rs778834918
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- REVEL 0.06
- MetaLR 0.15
- MetaSVM -0.98
- CADD 7.94
- PolyPhen-2 0.01
- SIFT 0.18
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.5e-05)
- Structural context available