S96F (p.Ser96Phe) variant of NLGN4X (Neuroligin-4, X-linked)
S96F (p.Ser96Phe) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
S96F (p.Ser96Phe) variant details
- p.Ser96Phe
- cosmic curated COSV10457
- gnomAD rs1220377209
- Missense
- Variant Prioritization Score for Impact Estimate 0.537
- REVEL 0.49
- MetaLR 0.50
- MetaSVM 0.24
- CADD 23.20
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available