S118T (p.Ser118Thr) variant of NLGN4X (Neuroligin-4, X-linked)
S118T (p.Ser118Thr) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S118T (p.Ser118Thr) variant details
- p.Ser118Thr
- ExAC rs764752836
- TOPMed rs764752836
- gnomAD rs764752836
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.11
- MetaLR 0.12
- MetaSVM -0.95
- CADD 7.58
- PolyPhen-2 0.00
- SIFT 0.60
- Most common in the Non-Finnish European population (allele frequency 2.4e-06)
- Structural context available