R117T (p.Arg117Thr) variant of NLGN4X (Neuroligin-4, X-linked)
R117T (p.Arg117Thr) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
R117T (p.Arg117Thr) variant details
- p.Arg117Thr
- gnomAD rs1206070204
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- REVEL 0.32
- MetaLR 0.11
- MetaSVM -1.02
- CADD 9.21
- PolyPhen-2 0.18
- SIFT 0.34
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available