Q5R (p.Gln5Arg) variant of NLGN4X (Neuroligin-4, X-linked)
Q5R (p.Gln5Arg) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
Q5R (p.Gln5Arg) variant details
- p.Gln5Arg
- TOPMed rs899519777
- gnomAD rs899519777
- Missense
- Variant Prioritization Score for Impact Estimate 0.0972
- REVEL 0.07
- MetaLR 0.07
- MetaSVM -1.02
- CADD 0.52
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Latino/Admixed American population (allele frequency 9.6e-05)
- Structural context available