P93S (p.Pro93Ser) variant of NLGN4X (Neuroligin-4, X-linked)
P93S (p.Pro93Ser) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
P93S (p.Pro93Ser) variant details
- p.Pro93Ser
- Ensembl rs867795084
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.34
- MetaLR 0.33
- MetaSVM -0.47
- CADD 14.10
- PolyPhen-2 0.02
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 3.8e-05)
- Structural context available