P90T (p.Pro90Thr) variant of NLGN4X (Neuroligin-4, X-linked)
P90T (p.Pro90Thr) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
P90T (p.Pro90Thr) variant details
- p.Pro90Thr
- gnomAD rs1473002369
- Missense
- Variant Prioritization Score for Impact Estimate 0.62
- REVEL 0.60
- AlphaMissense 0.37
- MetaLR 0.57
- MetaSVM 0.46
- CADD 22.90
- PolyPhen-2 0.99
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available