P61S (p.Pro61Ser) variant of NLGN4X (Neuroligin-4, X-linked)
P61S (p.Pro61Ser) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
P61S (p.Pro61Ser) variant details
- p.Pro61Ser
- ExAC rs764554652
- gnomAD rs764554652
- Missense
- Variant Prioritization Score for Impact Estimate 0.197
- REVEL 0.05
- MetaLR 0.14
- MetaSVM -0.89
- CADD 14.10
- PolyPhen-2 0.27
- SIFT 0.08
- Most common in the South Asian population (allele frequency 1.8e-05)
- Structural context available