P16S (p.Pro16Ser) variant of NLGN4X (Neuroligin-4, X-linked)
P16S (p.Pro16Ser) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
P16S (p.Pro16Ser) variant details
- p.Pro16Ser
- cosmic curated COSV52035
- TOPMed rs1289752129
- gnomAD rs1289752129
- Missense
- Variant Prioritization Score for Impact Estimate 0.268
- REVEL 0.23
- MetaLR 0.13
- MetaSVM -0.99
- CADD 13.00
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 1.9e-05)
- Structural context available