P11T (p.Pro11Thr) variant of NLGN4X (Neuroligin-4, X-linked)
P11T (p.Pro11Thr) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P11T (p.Pro11Thr) variant details
- p.Pro11Thr
- ExAC rs769097463
- TOPMed rs769097463
- gnomAD rs769097463
- Missense
- Variant Prioritization Score for Impact Estimate 0.24
- REVEL 0.23
- MetaLR 0.13
- MetaSVM -0.94
- CADD 14.30
- PolyPhen-2 0.01
- SIFT 0.07
- Most common in the REMAINING population (allele frequency 2.2e-05)
- Structural context available