N64T (p.Asn64Thr) variant of NLGN4X (Neuroligin-4, X-linked)
N64T (p.Asn64Thr) in NLGN4X (Neuroligin-4, X-linked) is a missense change. Clinical records from EBI and UniProt describe it as likely benign. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
N64T (p.Asn64Thr) variant details
- p.Asn64Thr
- ESP rs141720696
- ExAC rs141720696
- TOPMed rs141720696
- gnomAD rs141720696
- Likely benign
- Missense
- Variant Prioritization Score for Impact Estimate 0.298
- REVEL 0.13
- MetaLR 0.20
- MetaSVM -0.85
- CADD 16.70
- PolyPhen-2 0.08
- SIFT 0.03
- EBI: Likely benign
- UniProt: Likely benign
- Most common in the East Asian population (allele frequency 6.6e-05)
- Structural context available