L8V (p.Leu8Val) variant of NLGN4X (Neuroligin-4, X-linked)
L8V (p.Leu8Val) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
L8V (p.Leu8Val) variant details
- p.Leu8Val
- ExAC rs765825856
- gnomAD rs765825856
- Missense
- Variant Prioritization Score for Impact Estimate 0.0972
- REVEL 0.07
- MetaLR 0.08
- MetaSVM -1.00
- CADD 0.61
- PolyPhen-2 0.06
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.4e-06)
- Structural context available