L26P (p.Leu26Pro) variant of NLGN4X (Neuroligin-4, X-linked)
L26P (p.Leu26Pro) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
L26P (p.Leu26Pro) variant details
- p.Leu26Pro
- gnomAD rs1324541497
- Missense
- Variant Prioritization Score for Impact Estimate 0.432
- REVEL 0.44
- MetaLR 0.29
- MetaSVM -0.80
- CADD 23.40
- PolyPhen-2 0.74
- SIFT 0.06
- Most common in the Latino/Admixed American population (allele frequency 5.7e-05)
- Structural context available