K35R (p.Lys35Arg) variant of NLGN4X (Neuroligin-4, X-linked)
K35R (p.Lys35Arg) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
K35R (p.Lys35Arg) variant details
- p.Lys35Arg
- TOPMed rs2040163417
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.19
- MetaLR 0.10
- MetaSVM -1.02
- CADD 6.62
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.2e-06)
- Structural context available