I39T (p.Ile39Thr) variant of NLGN4X (Neuroligin-4, X-linked)
I39T (p.Ile39Thr) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
I39T (p.Ile39Thr) variant details
- p.Ile39Thr
- TOPMed rs1475006510
- gnomAD rs1475006510
- Missense
- Variant Prioritization Score for Impact Estimate 0.19
- REVEL 0.25
- MetaLR 0.09
- MetaSVM -1.04
- CADD 3.36
- PolyPhen-2 0.00
- SIFT 0.21
- Most common in the REMAINING population (allele frequency 4.3e-05)
- Structural context available