F88V (p.Phe88Val) variant of NLGN4X (Neuroligin-4, X-linked)
F88V (p.Phe88Val) in NLGN4X (Neuroligin-4, X-linked) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
F88V (p.Phe88Val) variant details
- p.Phe88Val
- ExAC rs758104645
- gnomAD rs758104645
- Missense
- Variant Prioritization Score for Impact Estimate 0.776
- REVEL 0.94
- MetaLR 0.85
- MetaSVM 0.90
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.5e-05)
- Structural context available