W2C (p.Trp2Cys) variant of NLGN3 (Neuroligin-3)
W2C (p.Trp2Cys) in NLGN3 (Neuroligin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
W2C (p.Trp2Cys) variant details
- p.Trp2Cys
- gnomAD X-71147755-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- REVEL 0.35
- CADD 27.20
- PolyPhen-2 0.89
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available