T17R (p.Thr17Arg) variant of NLGN3 (Neuroligin-3)
T17R (p.Thr17Arg) in NLGN3 (Neuroligin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
T17R (p.Thr17Arg) variant details
- p.Thr17Arg
- ExAC rs769930005
- TOPMed rs769930005
- gnomAD rs769930005
- Missense
- Variant Prioritization Score for Impact Estimate 0.291
- REVEL 0.27
- CADD 9.41
- PolyPhen-2 0.08
- SIFT 0.41
- Most common in the East Asian population (allele frequency 0.00017)
- Structural context available