T17M (p.Thr17Met) variant of NLGN3 (Neuroligin-3)
T17M (p.Thr17Met) in NLGN3 (Neuroligin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data and structural context.
T17M (p.Thr17Met) variant details
- p.Thr17Met
- cosmic curated COSV62442
- ExAC rs769930005
- TOPMed rs769930005
- gnomAD rs769930005
- Missense
- Variant Prioritization Score for Impact Estimate 0.186
- REVEL 0.08
- CADD 11.40
- PolyPhen-2 0.11
- SIFT 0.23
- Most common in the South Asian population (allele frequency 3.7e-05)
- Structural context available