T17K (p.Thr17Lys) variant of NLGN3 (Neuroligin-3)
T17K (p.Thr17Lys) in NLGN3 (Neuroligin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
T17K (p.Thr17Lys) variant details
- p.Thr17Lys
- ExAC rs769930005
- TOPMed rs769930005
- gnomAD rs769930005
- Missense
- Variant Prioritization Score for Impact Estimate 0.199
- REVEL 0.11
- CADD 10.40
- PolyPhen-2 0.03
- SIFT 0.30
- Most common in the South Asian population (allele frequency 1.9e-05)
- Structural context available