S21R (p.Ser21Arg) variant of NLGN3 (Neuroligin-3)
S21R (p.Ser21Arg) in NLGN3 (Neuroligin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
S21R (p.Ser21Arg) variant details
- p.Ser21Arg
- ESP rs139781549
- ExAC rs139781549
- TOPMed rs139781549
- gnomAD rs139781549
- Missense
- Variant Prioritization Score for Impact Estimate 0.429
- REVEL 0.32
- CADD 12.50
- PolyPhen-2 0.01
- SIFT 0.56
- Most common in the REMAINING population (allele frequency 0.00066)
- Structural context available