R97Q (p.Arg97Gln) variant of NLGN3 (Neuroligin-3)
R97Q (p.Arg97Gln) in NLGN3 (Neuroligin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
R97Q (p.Arg97Gln) variant details
- p.Arg97Gln
- gnomAD X-71148039-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.578
- REVEL 0.48
- CADD 27.20
- PolyPhen-2 0.66
- SIFT 0.04
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available
- Literature evidence available