P104L (p.Pro104Leu) variant of NLGN3 (Neuroligin-3)
P104L (p.Pro104Leu) in NLGN3 (Neuroligin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.78 / 1. The record also includes population frequency data and structural context.
P104L (p.Pro104Leu) variant details
- p.Pro104Leu
- ExAC rs774807691
- gnomAD rs774807691
- Missense
- Variant Prioritization Score for Impact Estimate 0.78
- REVEL 0.83
- CADD 25.80
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available