L22V (p.Leu22Val) variant of NLGN3 (Neuroligin-3)
L22V (p.Leu22Val) in NLGN3 (Neuroligin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
L22V (p.Leu22Val) variant details
- p.Leu22Val
- Ensembl rs2092376202
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.18
- CADD 15.60
- PolyPhen-2 0.19
- SIFT 0.18
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available