G80S (p.Gly80Ser) variant of NLGN3 (Neuroligin-3)
G80S (p.Gly80Ser) in NLGN3 (Neuroligin-3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.80 / 1. The record also includes population frequency data and structural context.
G80S (p.Gly80Ser) variant details
- p.Gly80Ser
- rs749579878
- ExAC rs749579878
- TOPMed rs749579878
- gnomAD rs749579878
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.796
- REVEL 0.86
- CADD 26.40
- PolyPhen-2 1.00
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the South Asian population (allele frequency 5.6e-05)
- Structural context available