E81D (p.Glu81Asp) variant of NLGN3 (Neuroligin-3)
E81D (p.Glu81Asp) in NLGN3 (Neuroligin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
E81D (p.Glu81Asp) variant details
- p.Glu81Asp
- ExAC rs748466850
- TOPMed rs748466850
- gnomAD rs748466850
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.09
- CADD 16.20
- PolyPhen-2 0.03
- SIFT 0.43
- Most common in the African/African-American population (allele frequency 3.3e-05)
- Structural context available