V66V (p.Val66Val) variant of NIPBL (Nipped-B-like protein)

Name: NIPBL V66V (p.Val66Val) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-10-09
License: https://catvariant.com/terms-of-use

V66V (p.Val66Val) in NIPBL (Nipped-B-like protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.

V66V (p.Val66Val) variant details

p.Val66Val
rs146033170
gnomAD 5-36955605-C-G
Synonymous
Variant Prioritization Score for Impact Estimate 0.264
CADD 8.96
Most common in the 1KG:GBR population (allele frequency 0.0057)
Structural context available
Cited in: Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American… (PMID 25741868)
Cited in: Free the data: one laboratory's approach to knowledge-based genomic variant classification and preparation for EMR… (PMID 23757202)