D59D (p.Asp59Asp) variant of NIPBL (Nipped-B-like protein)

Name: NIPBL D59D (p.Asp59Asp) variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-10-09
License: https://catvariant.com/terms-of-use

D59D (p.Asp59Asp) in NIPBL (Nipped-B-like protein) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.

D59D (p.Asp59Asp) variant details

p.Asp59Asp
rs2149599551
gnomAD 5-36955584-C-T
Synonymous
Variant Prioritization Score for Impact Estimate 0.296
CADD 9.75
Most common in the East Asian population (allele frequency 2.5e-05)
Structural context available
Literature evidence available