T90N (p.Thr90Asn) variant of NFKBIA (NF-kappa-B inhibitor alpha)
T90N (p.Thr90Asn) in NFKBIA (NF-kappa-B inhibitor alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
T90N (p.Thr90Asn) variant details
- p.Thr90Asn
- TOPMed rs954063319
- gnomAD rs954063319
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.14
- MetaLR 0.28
- MetaSVM -0.52
- CADD 23.40
- PolyPhen-2 0.12
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 4.4e-05)
- Structural context available