P16T (p.Pro16Thr) variant of NFKBIA (NF-kappa-B inhibitor alpha)
P16T (p.Pro16Thr) in NFKBIA (NF-kappa-B inhibitor alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
P16T (p.Pro16Thr) variant details
- p.Pro16Thr
- TOPMed rs1439671395
- gnomAD rs1439671395
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.36
- AlphaMissense 0.08
- MetaLR 0.23
- MetaSVM -0.65
- CADD 18.00
- PolyPhen-2 0.15
- Population evidence available
- Structural context available