D35Y (p.Asp35Tyr) variant of NFKBIA (NF-kappa-B inhibitor alpha)
D35Y (p.Asp35Tyr) in NFKBIA (NF-kappa-B inhibitor alpha) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.82 / 1. The record also includes population frequency data and structural context.
D35Y (p.Asp35Tyr) variant details
- p.Asp35Tyr
- Ensembl rs2138834209
- Missense
- Variant Prioritization Score for Impact Estimate 0.818
- REVEL 0.80
- MetaLR 0.83
- MetaSVM 0.87
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.01
- Population evidence available
- Structural context available