Y5N (p.Tyr5Asn) variant of NFKB2 (Q00653)
Y5N (p.Tyr5Asn) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
Y5N (p.Tyr5Asn) variant details
- p.Tyr5Asn
- TOPMed rs1455622222
- gnomAD rs1455622222
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- AlphaMissense 0.12
- MetaLR 0.15
- MetaSVM -0.97
- CADD 28.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the East Asian population (allele frequency 5e-05)
- Structural context available