Y15H (p.Tyr15His) variant of NFKB2 (Q00653)
Y15H (p.Tyr15His) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
Y15H (p.Tyr15His) variant details
- p.Tyr15His
- gnomAD 10-102396274-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.521
- MetaLR 0.14
- MetaSVM -0.87
- CADD 26.40
- PolyPhen-2 0.80
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available