V41M (p.Val41Met) variant of NFKB2 (Q00653)
V41M (p.Val41Met) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
V41M (p.Val41Met) variant details
- p.Val41Met
- ExAC rs745622070
- TOPMed rs745622070
- gnomAD rs745622070
- Missense
- Variant Prioritization Score for Impact Estimate 0.67
- CADD 24.60
- PolyPhen-2 0.93
- SIFT 0.19
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available