S3N (p.Ser3Asn) variant of NFKB2 (Q00653)
S3N (p.Ser3Asn) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data and structural context.
S3N (p.Ser3Asn) variant details
- p.Ser3Asn
- ExAC rs778625681
- TOPMed rs778625681
- gnomAD rs778625681
- Missense
- Variant Prioritization Score for Impact Estimate 0.685
- CADD 16.20
- PolyPhen-2 0.00
- SIFT 0.27
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available