S3I (p.Ser3Ile) variant of NFKB2 (Q00653)
S3I (p.Ser3Ile) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
S3I (p.Ser3Ile) variant details
- p.Ser3Ile
- ExAC rs778625681
- TOPMed rs778625681
- gnomAD rs778625681
- Missense
- Variant Prioritization Score for Impact Estimate 0.702
- CADD 18.60
- PolyPhen-2 0.01
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available