S22F (p.Ser22Phe) variant of NFKB2 (Q00653)
S22F (p.Ser22Phe) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
S22F (p.Ser22Phe) variant details
- p.Ser22Phe
- gnomAD 10-102396296-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.445
- MetaLR 0.07
- MetaSVM -1.00
- CADD 20.70
- PolyPhen-2 0.03
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available