S115W (p.Ser115Trp) variant of NFKB2 (Q00653)
S115W (p.Ser115Trp) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data, published literature, and structural context.
S115W (p.Ser115Trp) variant details
- p.Ser115Trp
- gnomAD 10-102397004-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.565
- MetaLR 0.17
- MetaSVM -0.84
- CADD 27.60
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available