P7L (p.Pro7Leu) variant of NFKB2 (Q00653)
P7L (p.Pro7Leu) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.57 / 1. The record also includes population frequency data and structural context.
P7L (p.Pro7Leu) variant details
- p.Pro7Leu
- ExAC rs760413992
- gnomAD rs760413992
- Missense
- Variant Prioritization Score for Impact Estimate 0.572
- CADD 23.30
- PolyPhen-2 0.12
- SIFT 0.21
- Most common in the Latino/Admixed American population (allele frequency 6.6e-05)
- Structural context available