L9R (p.Leu9Arg) variant of NFKB2 (Q00653)
L9R (p.Leu9Arg) in NFKB2 (Q00653) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data, published literature, and structural context.
L9R (p.Leu9Arg) variant details
- p.Leu9Arg
- gnomAD 10-102396257-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.55
- MetaLR 0.16
- MetaSVM -0.79
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available